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MHRA alert - diclofenac injection recall

27th May 2010

Dyloject vials (diclofenac 75mg/2mL) have been recalled in the UK due to possible contamination with small amounts of white particles. The particles are not readily visible and work is ongoing to determine the nature, size and risk posed by this contamination. More information including a full list of batch numbers can be found on the MHRA website (see link below).

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Prucalopride launched in UK for chronic constipation in women

4th May 2010

Prucalopride (Resolor, Movetis) has been launched in the UK for the symptomatic treatment of chronic constipation in women in whom laxatives fail to provide adequate relief. The drug is a novel enterokinetic agent acting via selective high affinity 5-HT4 receptor antagonism. The National Institute for Health and Clinical Effectiveness (NICE) are expected to issue guidance on this product in December 2010.
The recommended dose is 2mg daily (1mg in severe renal or hepatic impairment), elderly patients should start on 1mg daily, increasing to 2mg daily, if needed.
The cost of 28 days @ 1mg or 2mg daily = £38.69 and £59.52 respectively.

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FDA launches initiative to reduce infusion pump risks

4th May 2010

The US Food and Drug Administration have announced a new initiative to address safety problems associated with external infusion pumps and is moving to establish additional premarket requirements for infusion pumps. There is also a new webpage devoted to infusion pump safety including strategies for risk reduction.

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